Search on: INTRINSICALLY DISORDERED PROTEINS 
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Descriptor English:   Intrinsically Disordered Proteins 
Descriptor Spanish:   Proteínas Intrínsecamente Desordenadas 
Descriptor Portuguese:   Proteínas Intrinsicamente Desordenadas 
Synonyms English:   Natively Unfolded Proteins
Unstructured Proteins  
Tree Number:   D12.776.481
Definition English:   Functional proteins that do not have unique, stable, folded, three-dimensional native structures or that possess non-ordered regions under physiological conditions. They are characterized by extraordinary structural flexibility and plasticity, which enable them to adopt different conformations in response to different stimuli or different interactions. 
See Related English:   Protein Folding
Protein Unfolding
 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55331 
Unique Identifier:   D064267 

Occurrence in VHL:
 

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